NO DRUGS

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Full List of all known drugs -which are  to be avioded in

Mast cell conditions .

- ABSOLTE NO's

 

Radiographic contrast - esp CT contrast and when used for angiograms

 

Opites -esp morphine, codines , fentnyl , pethedine

 

Dextran /Dextrin -In plasma expander fluids /colloids  ,eyedrops and foods

 

Alochol - ethanol as preservative

 

Mycin antibiotics - antibiotic drug name which ends in mycin

 

Beta blockers - bring on reactions and interact with epinepeherine ( by working on alpha receptors- deepen ing hypotension (low blood pressure ) and bradycardia (Low pulse ) . The drug name of beta blockers- end in OL - sotalol , bisoprolol

SSRI's /SSNI's

Cause increase in serotonin and it can already be high in many .So ssri's /ssni can cause serotonin syndrome

 

Heparin -activates mast cells .also injection with high - Chondroitin Sulfate and or alcohol

 

Muscle relaxants - Pancuronium, alcuronium, D-tubocurarine

 

Narcotics - Thiopental

 

Analgetics - Morphine, pethidine, nonsteroidal anti-inflammatory drugs (NSAIDs), acetylsalicylic acid (aspirin), metamizole

 

Local anesthetics - Prilocaine

 

Antihypotonics - Dobutamine

 

Antihypertensive drugs - Verapamil, alprenolol, dihydralazine

 

Antiarrhythmics - Propafenone

 

Diuretics - Amiloride (water tablets )

 

Drugs influencing gut motility - Metoclopramide (antisickness)

 

Antibiotics - Cefuroxime, cefotiam, -Ceftriaxones -(10% cross over with penicillin so not given if patient penicillin anaphylaxis )

 

isoniazid, (Laniazid, Nydrazid), TB treatment

 

Pentamidin,

Antiprotozoal agent effective in Trypanosomiasis, Leishmaniasis, and some fungal Infections; used in treatment of Pneumocystis Pneumonia in HIV-infected Patients. It may cause Diabetes Mellitus, Central Nervous System damage, and other toxic effects.

 

clavulanic acid, - In Augmentin - co amociclav

 

chloroquine

 

Polymixin and assoc - PolysporinNeosporinPolymyxin BPolymyxin E

found often in eye and ear drops

 

Amphoteractin -(Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec

 

Mucolytics - Acetylcysteine, ambroxol

 

Broncholytics - Aminophylline ( emergency asthma treatment) daily version theophylline

 

H2-receptor antagonists

Cimetidine

(interacts with statins and other drugs )

 

Cytostatics - Cyclophosphamide

 

Antidepressants - Amitriptyline

Epipen interactions

 

Beta blockers - cause alpha recpetor responses - low pulse ,lower BP , airway spasm .

 

MOAI's

 

Tricyclic antidepressants - amitryptylline ,Nortryptylline

Caution with other ingredients  - commonly including -

corn flour /maize starch

sweetners - malt o dextrin , a sulpahmine K ,

sodium leureth sulphate

maltilol

asparthamine

mannitol

lactose

gelatine

sulphite preservatives

e200-228 and e160 a-d

vinigar

alochol

 

each person has different issues

Affects some but not others -

 

Sulphur based medictions inc antibiotics - best place to check if amedicine is asulphur base - wikipedia -it has the chemical name on the right hand side of the page .

Known drugs -

Diamox - used in EDS ,is sulphur based and has caused anaphylaxis

Frousamide - diuretic

 

Quinoline antibiotics - levoquin , ciprofloxicillin . Also strong so i advise having probiotic drinks alongside these . http://www.ncbi.nlm.nih.gov/pmc/articles/PMC115209/

 

Sources

 

BNF online

 

http://www.tmsforacure.org/research.php

 

http://www.iainfoctr.com/articles/histamine.php